does tirzepatide affect your heart Effects of tirzepatide, a dual GIP and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats Can tirzepatide, a long-acting agonist

Decisions about temporarily holding tirzepatide during acute significant gastrointestinal illness should be made based on clinical judgment and the severity of symptoms

Prior authorization for Wegovy typically requires documented obesity (BMI 30) or overweight with comorbidity, plus evidence of previous lifestyle intervention attempts

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Three patients reported adverse side effects

The most commonly reported adverse effects are gastrointestinal , including: Nausea Bloating and flatulence Diarrhoea (particularly at higher doses above 12 g daily) Abdominal discomfort These effects are typically mild and often resolve with continued use or dose reduction