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CFU (colony-forming units) is a rough measure of living organisms

The bacteria in your gut ferment fiber into SCFAs (which trigger GLP-1), and specific probiotic strains have been shown to directly enhance GLP-1 secretion from L-cells

Adults with type 2 diabetes (T2D) and obesity lose less weight on EVERY GLP-1 drug compared to those without diabetes, consistently ~5% less

Some individuals experience reduced efficacy over time, requiring dose increases to maintain suppression of appetite and metabolic effects

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