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Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder
Abstract Neurodegenerative diseases are characterized by progressive neuronal dysfunction, often accompanied by chronic inflammatory states and redox imbalance within the central nervous system (CNS)
PMID 4161213
It can also contribute to the development of muscle disorders
Eumelanin/Pheomelanin Ratio Research Research suggests that defective MC1R signaling resulting from receptor gene mutations may shift pigmentation toward pro-oxidant pheomelanin at the expense of eumelanin in preclinical models
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