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Because we just dont know yet exactly what the long-term outcomes are for people who become pregnant while taking these medications. One early study suggested that using GLP-1 agonists during the first trimester didnt harm fetal development

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Statistical analysis A sample size of 300 participants provided an effective power of at least 96% for the two co-primary endpoints, and at least 43% for all confirmatory secondary endpoints, which were tested in a predefined hierarchical order (Supplementary Table 4)

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