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Abstract Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used to improve glycemic control and induce weight loss in individuals with type 2 diabetes (T2D), yet treatment responses vary significantly among individuals

Sepsis induces microvascular changes in the endoneurium, increasing vascular permeability and allowing toxic factors to infiltrate nerve endings (13,93)

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[Updated 2019 Jul 16]

In the 72-week SURMOUNT-5 obesity trial, tirzepatide produced an average body-weight reduction of 20.2%, compared with 13.7% for semaglutide