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These results suggest that mild to moderate hyperglycemia is required for the insulinotropic effect of GIP in nondiabetic subjects, acting as a mechanism to prevent reactive hypoglycemia following the consumption of fatty foods

Intranasal delivery, though less studied with Dihexa, would theoretically provide direct CNS access with minimal systemic exposure, potentially requiring the least frequent administration to maintain effective brain tissue concentrations

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Dyslipidemia: A combination therapy of L-carnitine 2 g once daily with orlistat in adults with type 2 diabetes