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The researchers noted several important limitations, including the retrospective observational design, inability to verify medication adherence, and potential residual confounding despite propensity matching

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The authors summarize the findings from phase 1, 2, and 3 clinical trials, which demonstrated that tirzepatide effectively controls blood sugar levels, improves insulin sensitivity, aids in weight loss, and positively influences lipid metabolism in patients with type 2 diabetes

A provider can explain what to expect, how to take the medication correctly, what side effects may happen early on, and when dose adjustments may or may not make sense