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Figures Abstract Background Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide have been shown to induce substantial weight loss and improve cardiometabolic risk factors in patients living with obesity

262 In gout, the release of IL-1 mediated by inflammasomes triggers a significant inflammatory response characterized by vasodilation and rapid recruitment of neutrophils to the site of crystal deposition, thereby driving acute inflammatory episodes

Other Precautions: Long-term use may reduce zinc levels

Dehydration-related acute kidney injury has been reported, particularly in older adults and those with baseline renal impairment