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Rog Z, Kamiska K, Paczyszyn-Trzewik P, Sowa-Kuma M

Future approaches While possible biomarkers for PD in classical studies have been hypothesis-driven, attempts to develop effective procedures for the differential diagnosis of PD in its early stages have led to the performance of CSF multianalyte methods including systematic measurements of patterns of variation in proteins (proteomics) or small molecules (metabolomics)

Among these BDPs, a dodecapeptide segment of BDNF aa 104-115 (BDP-12, IDTSCVCTLTIK) was identified as the key fragment responsible for rBDNF-rLRR interaction by using immunoprecipitation-MALDI-TOF analysis (Fig

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