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FDA labeling does include a warning about acute kidney injury in the postmarketing setting, often associated with severe gastrointestinal adverse reactions leading to volume depletion

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However, the extent and longevity of weight loss achieved with these therapies may vary from patient to patient

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The Company concluded the Agreement is not within the scope of Accounting Standards Codification 808, Collaborative Arrangements as the Company does not share equally in the exposure to significant risk

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Rdiger, Effect of orlistat on blood cyclosporin concentration in an obese heart transplant patient

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