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To address the challenges mentioned and promote the clinical translation of ROS-targeted agents, we could improve drug absorption and distribution by optimizing the chemical structure of the drug or using delivery systems like nanoparticles

Kalincik, T

By providing an exogenous source of fumarate, this specific supplement formulation acts as a direct catalyst for the Krebs cycle

However, challenges such as oxidative stress and inflammation significantly limit the efficacy of bone marrow MSC transplantation therapy

Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes