Even when weight-related use is approved, many plans require prior authorization, documentation of previous weight-loss attempts, or specific lab results
Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ et al (2003)
Neurology (2003) 61:50615.10.1212/01.WNL.0000078939.64774.1B 96 RamaekersVTSequeiraJMArtuchRBlauNTemudoTOrmazabalAet alFolate receptor autoantibodies and spinal fluid 5-methyltetrahydrofolate deficiency in Rett syndrome
Pens removed from refrigeration: if you take a pen out of the refrigerator (for travel or room-temperature storage), it's good for 21 days at room temperature (up to 86F / 30C)
Some mild side effects reported include nausea, diarrhea, and stomach discomfort, but these tend to subside over time as the body adjusts to the medication