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J., Ozols, E., Atkins, R
These benefits were highlighted in 2019 when the Lancet published a meta-analysis of seven clinical trials showing that these treatments reduced hospital admission by 9%, all-cause mortality by 12% and deaths associated with kidney disease by 17% (Wilding et al., 2021)
Glucagon-like Peptide-1 receptor agonists and hepatic decompensation events in patients with cirrhosis and diabetes
Dropping the 1mg arm acknowledges that while it produced statistically significant weight loss, the magnitude was insufficient for a competitive regulatory filing
doi: 10.1056/NEJMoa1509225
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