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For a scientific overview of the microbiome, the difference between GLP-1 agonist drugs and microbial approaches to regulating GLP-1, and the role GLP-1 plays in helping to maintain a healthy weight, please refer to the white paper: Harnessing GLP-1 in the digestive tract for better metabolic health

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In a small study of 20 people with obesity, GLP-1 drugs restored the function of natural killer (NK) cells, a part of the immune system that helps destroy cancer cells

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But for selected patients, thoughtful hormone evaluation may be part of a broader plan to support sleep, body composition, sexual health, energy, bone, mood, and quality of life

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Mechanistically, in macrophages, GLP-1RAs directly ameliorate NF-B activation, thereby improving insulin resistance [132]

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