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Hum Reprod 33(9):16021618

Chief among those concerns are side effects, with 51% of respondents citing current side effects such as nausea, vomiting, headaches, and more as a top concern when it comes to GLP-1 medications, while 40% said they are worried about potential long-term side effects that may develop with use

It has been proposed that GIP regulates inflammation and leukocyte adhesion through endothelin 1 while promoting vasodilation via nitric oxide secretion [109]

See our side effect comparison for a detailed breakdown

And there are also obesity-related cancers, so Low Wang said it makes sense that if people control their diabetes and lose significant amounts of weight, their risks of getting cancer will also decline