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GLP-1 receptor agonists like Semaglutide (Ozempic) and Tirzepatide (Mounjaro) cause the most significant weight loss among all diabetes medications

Efficacy, tolerability, and safety of TRPC4/5 inhibitor BI 1358894 in patients with major depressive disorder and inadequate response to antidepressants: A Phase II randomized, placebo-controlled, parallel group, dose-ranging trial

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The research underlines the complexity of receptor interactions with research peptides and the importance of carefully analyzing receptor activities in different species to avoid unwanted GI side effects