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[10] [11] The lack of IGF-1 (or inhibition of IGF-1R) causes impaired cellular morphogenesis to occur, which prevents lipids from being secreted in some keratinocytes that build out the lamellar bilayer of the skin at the SC-SG interface around the follicles

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The standard response value for the von Frey test is 5.010.0 g, and the normal response value for the thermal test is 59 s

1-2, ISSN 1479-6805.