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The secondary outcomes were the change of mean arterial blood pressure (delta MAP, %), the kinetics of arterial blood pressure, gap CO 2 , gap CO 2 /oxygen arteriovenous difference ratio, oxygen delivery (DO 2 ), oxygen consumption (VO 2 ), arterial lactate, hematocrit, sodium, and chloremia over a period of 60 min

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Patients should always report any side effects they experience, especially if they are severe or do not go away