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Because people on GLP-1s have reduced appetites and sometimes nausea, that can lead to underfueling, Wenger said

10.2147/IJN.S496664 94 LiJ.LuoT.WangD.ZhaoY.JinY.YangG.et al (2025)

It depends on the active compound within You just mentioned a 5mg vial and a 5ml vial

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Strategies that help: Hydrate aggressively during flights (the cabin air is extremely dry) Eat bland, familiar foods on travel days Avoid fatty foods, which worsen GLP-1 nausea Pack safe snack options in your carry-on Avoid alcohol on travel days (amplifies dehydration and GI effects) Fatigue and jet lag GLP-1 fatigue is a real side effect that compounds with jet lag