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Its the active ingredient in the antidepressants Wellbutrin and Aplenzin, and in the smoking-cessation aid Zyban

Availability of data and materials The dataset supporting the conclusions of this article is included within the article (and its additional file)

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After the study, it was observed that APS intervention significantly upregulated hippocampal Nrf2 gene expression, total Nrf2 protein levels, and nuclear translocation in depressed rats

Hence, abnormal amino acid metabolism has diverse and important roles in various cancers, and the potential impact of metabolic control and regulation in the tumor microenvironment is becoming increasingly important