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10.1016/j.tibtech.2011.01.008 59 WangZ.Colombi CiacchiL.WeiG

Role of reactive oxygen species in cell signalling pathways

Captured z-series were imported and analyzed using Image J

Statistical Analysis Data are expressed as meanstandard deviation

In contrast, in normal non-cancer rectal tissue, metformin significantly altered the secretion of only three IL-17 related cytokines, suggesting that metformin differentially alters the inflammatory secretome of normal rectal tissue, when compared to rectal cancer tissue, which may support its potential utility as a radiosensitiser