So many healthy drinks sacrifice flavor for macros, but the Gladiator
An RCT of 174 patients with severe alcoholic hepatitis found that the combination of prednisolone + NAC (IV for 5 days, then oral for 2 weeks) significantly reduced 1-month mortality compared to prednisolone alone (8% vs 24%, p=0.006), though the difference was not significant at 6 months (Nguyen-Khac et al., N Engl J Med, 2011) [36]
Continued use of these models, including newer ones like gut organoids with human microbiota or brain-gut chip systems, will allow dissection of how specific microbes or metabolites act on specific brain cell types
This followed earlier FDA warning letters to compounding pharmacies that marketed BPC-157 products with therapeutic claims
Br J Rheumatol 29(5):404405 Wispriyono B, Matsuoka M, Igisu H, Matsuno K (1998) Protection from cadmium cytotoxicity by N-acetylcysteine in LLC-PK1 cells