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Block randomization and allocation concealment was done using sequentially numbered, opaque sealed envelopes (SNOSE) and monitored by the central coordinator

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Antioxidant mechanisms include enhanced expression of molecules that can modulate ROS accumulation by both enzymatic and nonenzymatic meansGlutathione (GSH) is an antioxidant that acts as a free radical scavenger and a detoxifying agent in cells

Although, our finding that semaglutide can decrease withdrawal-like symptoms in animals trained under short-access conditions is similar to other findings that liraglutide, another GLP-1 receptor agonist, can decrease symptoms of nicotine withdrawal [52]