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M., Reimann, F., & Blottire, H

Some people may experience light headaches during the first week

Its important to know that oral semaglutide has to be taken on an empty stomach with a small amount of water, at least 30 minutes before any food, drink, or other medications to maximize absorption, Dushay says

Some individuals may experience temporary food sensitivities during treatment, though there is no established link between GLP-1 medications and permanent food intolerances

More serious but rare side effects include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Changes in heart rate While these serious complications are uncommon, they underscore why these drugs require medical supervision