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Urine and fecal samples were collected from each rat at 08, 824, 2448, and 4872 h

This activates a signaling pathway within the cell that promotes the expression and synthesis of collagen genes

They activate the G-protein coupled receptor GPR120 and peroxisome proliferator-activated receptor gamma (PPAR), leading to inhibition of NF-B nuclear translocation and reduced transcription of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6 in macrophages and hepatic immune cells

Different B12 injections

Additionally, the increased MDA levels observed upon SYNCRIP depletion were significantly reduced following SYNCRIP restoration (Figure 3E-G), further linking SYNCRIP function to suppression of ferroptosis