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1.3.2 The pharmacological-interaction concept Notwithstanding the early proposal of hapten formation as a mechanism of drug hypersensitivity, several non-reactive drugs, or diagnostic agents, such as radiocontrast media, have been known to induce adverse immune reactions in a manner non-conformant with the hapten model

In January, the first GLP-1 receptor agonist, semaglutide (Ozempic, Novo Nordisk), was approved by the FDA for use by adults with type 2 diabetes and chronic kidney disease to reduce the risk for worsening CKD and kidney failure

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