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In hepatocellular carcinoma (HCC) studies, ADI-PEG-20 has been shown in early clinical trials to make HCC animal models and patients more sensitive to FOLFOX chemotherapy through arginine depletion

Stay hydrated with small sips of water, unsweetened tea, or electrolyte drinks throughout the day, but avoid drinking large amounts with meals

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First of all, the size of the GI tract, especially the stomach, is reduced, causing patients to eat less