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[20] It is also popular as an add-on medication in the cases of "incomplete response" to the first-line selective serotonin reuptake inhibitor (SSRI) antidepressant

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Additionally, inflammatory factors such as TNF-, IL-6, CRP, IL-12, IFN-, and NLRP3 inflammasome were elevated in various tissues, including those in the ovaries and follicular fluid (FF), adipose tissue, endometrium, intestine and liver ( Figure 2 )