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In a recent news release, the manufacturer announced the submission of a new drug application to the US Food and Drug Administration (FDA) and a marketing authorisation application to the European Medicines Agency (EMA) for tirzepatide for the treatment of adults with type 2 diabetes [12]

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What is fascinating is that their effects are not limited to alcohol: preclinical and correlational data indicate possible benefits in decreasing use of nicotine and opioids, which makes sense as alcohol, cannabis, opioid, and nicotine use disorders cluster together genetically into one brain disorder

Semaglutide, suicidal ideation and behaviour: a resting state functional magnetic resonance imaging perspective