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This was a singlecenter, interventional, openlabel, proofofconcept study where 24 patients with AT were treated with NR (25 mg/kg bodyweight per day) during four consecutive months and subsequently followed during 2 months without treatment

Standardized outcome measurement facilitates assessment of individual patient response and contributes to broader understanding of clinical efficacy

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For research protocols that require multiple accesses to a vial, bacteriostatic water is strongly preferred

Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial