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Our most advanced candidate, danuglipron, has shown good efficacy in a twice-daily formulation, and we believe a once-daily formulation could be highly competitive in the oral GLP-1 space, said Mikael Dolsten, MD., PhD., Chief Scientific Officer & President, Pfizer Research and Development

Both are copper peptides, but AHK-Cu swaps glycine for alanine in its amino acid chain (alanine-histidine-lysine vs glycine-histidine-lysine)

Wegovy is not recommended for use by anyone with: a personal or family history of MTC multiple endocrine neoplasia syndrome type 2 (MEN2), a rare condition that causes tumors in certain glands, including the thyroid a history of allergic reaction to the medication or any of its ingredients severe gastroparesis, a chronic condition characterized by delayed stomach emptying How is Wegovy administered in SLD