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47,239 Based on the recruited adapter proteins, TLR signaling pathways have been classified into two distinct categories: MyD88-dependent (in all TLRs except TLR3) and MyD88-independent (also known as the TIR domain-containing adapter-inducing interferon- (TRIF)-dependent pathway)

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20 For example, in cats with hepatic lipidosis, approximately 25% will have an increased prothrombin time (PT), 35% will have an increased partial thromboplastin time (PTT), but 60% of cats will have increased PIVKA (proteins induced by vitamin K antagonists or absence)