Thus these findings demonstrate the important role of GSH to maintain intestinal morphology and function, and that, at least, in the TNBS+ethanol-induced colitis, mucosal damage is caused by both depletion of GSH and ROS generation
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The reduction in GSSG levels might represent a distinct pathophysiological state in acute relapse, possibly involving different mechanisms from those in first-episode or stable phases of the illness [32]
Copenhagen, The Nordic Cochrane Centre) [27]