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However, this study has notable clinical limitations: The second cohort (Cohort 2) only included 24 patients, confounding factors such as diet and concurrent medications were not adjusted for, and there is a lack of clinically standardized protocols for MDSC function detection

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[21] Neurological symptoms: Sensory or motor deficiencies (absent reflexes, diminished vibration or soft touch sensation), subacute combined degeneration of spinal cord, or seizures

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