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doi:10.1016/S0969-2126(01)00206-4

GLP-1RAs improve hyperglycemia by enhancing insulin secretion through increases in -cell cytoplasmic cyclic adenosine monophosphate [53], which activates protein kinase A (PKA) and, thus, increases in intracellular calcium and triggers insulin exocytosis in a glucose-dependent manner [54]

Hypokalemia and sudden death may occur in severe megaloblastic anemia which is treated intensely

(Article in Korean) Bellinghieri G, Savica V, Barbera CM, et al

Chemical synthesis and subsequent in vivo evaluation of a GIP/GLP-1MK-801 co-agonist conjugate revealed enhanced weight loss in DIO mice compared with mice treated with the GIP/GLP-1 co-agonist alone (Extended Data Fig