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Specifically, increased expression of peroxisome proliferator-activated receptor- coactivator-1 protein, a key regulator of mitochondrial biosynthesis, disrupts the mitochondrial structure and leads to dysfunctional proliferation, which is involved in the development of certain cardiac diseases, such as heart failure and atherosclerosis (45)

and premature ovarian aging are common causes of female infertility, but some cases are unexplained (idiopathic)

PMID: 37110608 Sci Rep Chemotherapeutic hormesis induced by the tumor microenvironment in refractory ovarian cancer

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