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10.1007/s11064-008-9739-0 123

Neuropsychopharmacology 16 , 167170 (1995)

The dichloroquinoxaline group extends to ICL3 forming nonpolar interactions with K346 6.35b , C347 6.36b and a cholesterol molecule in TM6, introduction of electron-donating substituents or replacement of quinoxalines by benzimidazole or quinoline at C-6 and C-7 positions led to poor tolerance 38