doi: 10.1111/ijpo.12131 199 MuscogiuriGBarreaLFaggianoFMaiorinoMIParrilloMPuglieseGet al
The once-weekly injectable was originally used to help manage diabetes but gained FDA approval in 2021 for "chronic weight management." It suppresses appetite by balancing out the body's hunger hormones and delaying digestion, and has been shown to lead to a 15% to 20% loss of body weight over 68 weeks, Insider's Gabby Landsverk previously reported
After 26 weeks, the levels of hs-CRP and endothelin-1 decreased (27.5% and 18.75%, respectively) in the exenatide arm whereas the levels of fibrinogen, monocyte chemoattractant protein-1, leptin and endothelin-1 increased in the insulin glargine arm (13.4%, 30.2%, 47.5%, and 80%, respectively) [45]
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