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linagliptin, CARMELINA) show that DPP-4 inhibitors are not associated with any risk of major adverse cardiovascular events
In a systematic review of seven randomized controlled trials for people with type 2 diabetes published in Diabetes Therapy, researchers compared the efficacy data of GLP-1 injectable medications to the oral semaglutide pill
Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025
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Aligning the timing of ovulation induction, IUI (intrauterine insemination) or IVF with the medication plan
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