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Hepatic taurine synthesis is largely restricted by the low availability of cysteinesulfinate as substrate for cysteinesulfinate decarboxylase, and taurine production is increased when cysteinesulfinate increases in response to an increase in the hepatic cysteine concentration and the associated increase in cysteine dioxygenase activity (Stipanuk 2004)

Several anemia codes map to HCCs, including D61.9, D61.01, and D64.81, depending on the CMS risk adjustment model

Functional joint and tendon improvements reduced pain under load, improved range of motion require sustained dosing for 48 weeks minimum, with peak structural repair effects occurring at 812 weeks

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