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Authors' contributions JMC participated in the coordination of the study, statistical analysis and interpretation of data, and helped to draft the study

Patients often report significant reductions in pain and swelling within the first one to two weeks , with measurable improvements in range of motion following shortly after

Archived from the original on April 30, 2020

Cantin et al., 1987)

Importantly, elevated KYNA in the CNS may contribute to cognitive deficits in schizophrenia by antagonizing 7nAChRs and NMDARs, which are critical for synaptic plasticity, working memory, and cortical network coordination [76, 240,241,242]