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The tricky part is that it doesnt always feel dramatic

Data backs this up, with one study finding that side effects and cost were two of the top contributors of patients who stopped taking GLP-1s for overweight or obesity within the first year of starting

A study in The New England Journal of Medicine found that just 33% of the dose drove 72% of the weight loss at week 72 with a lower side effect profile

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Published mouse studies did not report overt toxicity, liver-enzyme issues, or sickness-related weight loss at 25-50 mg/kg IP for up to 8 weeks