can glutathione cause heart problems blood decreases in chronic diseases deficiency and failure: a systematic review of human and animal evidence Frontiers Is Glutathione the Master Antioxidant?

can also accelerate aging-related inflammatory processes

The amount of magnesium in the brain is highly stable and declines more slowly than in other tissues, so when small decreases happen, it influences neuronal functioning significantly

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Studies consistently measure reduced glutathione levels in older adults and in chronic disease states, suggesting that maintaining adequate levels may be a key factor in cellular resilience

Nat Rev Clin Oncol