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reported in approximately 4060% of participants in higher-dose groups Vomiting reported in approximately 2030% of participants at higher doses Diarrhoea Constipation Decreased appetite (which, whilst contributing to weight loss, can also be uncomfortable) The majority of gastrointestinal events were mild to moderate in severity and tended to diminish over time as participants adjusted to the medication

Because of Novo Nordisks patents, generic semaglutide products will not be able to enter the U.S

In addition, aggressive marketing by digital health companies has positioned GLP-1 drugs as both metabolic and lifestyle solutions