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Paeoniflorin also inhibits neuroinflammation and improves BIPN by decreasing IL-6 levels and modulating PARKIN-mediated mitochondrial autophagy (Sun et al., 2022)
For patients suffering from debilitating fatigue and post-exertional malaise (PEM), this cellular-level energy support is critical
Many trials recruited participants with skin conditions or utilized intravenous administration routes, which fall outside our criteria for oral supplementation in healthy individuals
It should be avoided by pregnant women (as it may induce labor), individuals with inflammatory bowel conditions, or those with abdominal pain of unknown origin
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