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Methods Enzymol 252:3853 Xiong CH, Xia YL, Zheng P, Wang CS (2013) Increasing oxidative stress tolerance and subculturing stability of Cordyceps militaris by overexpression of a glutathione peroxidase gene

This represents direct evidence of the mechanism at the cellular level, though its translation to clinical longevity outcomes in humans continues to be studied

in 2020 showed no improvement in the CPR (OR = 1.15, 95% CI = 0.95 140) or LBR (0.94, 95% CI = 0.41- 2.15) when AOXs were given to women treated with IVF or ICSI (188)

At concentrations as low as 0.11 ng/mL, endotoxins can activate innate immune pathways in mammalian cells including NF-B and inflammasome signaling which directly confound any study involving cytokine release, cell viability, differentiation, or proliferation

Skeletal health is a major concern during rapid weight loss