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It works by mimicking a hormone called ghrelin, which signals the pituitary gland to release growth hormone in a safe, controlled way

However, they are legally available for research purposes and are used off-label by doctors

For perimenopausal women experiencing accelerated skin aging due to declining estrogen, GHK-Cu represents a scientifically plausible optionparticularly in topical formulations where safety data is more established

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From a research perspective, it is a reference study for understanding human pharmacology of melanocortin agonists