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These metabolites, which exhibited hub-like behavior at baseline, showed comparatively lower connectivity following the dietary intervention, suggesting a modulation of pathway-level interactions rather than complete network reorganization

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Another important process underlying ferroptosis depends on the interplay between lipid peroxidation and antioxidant defense mechanisms [2]

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For context, semaglutide and tirzepatide do not produce dysesthesia at clinically significant rates, though a recent paper in PMC examined allodynia and dysesthesia reports across GLP-1 medications more broadly