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Symptoms of acid reflux can vary widely but often include: Heartburn, a burning sensation in your chest Regurgitation of food or sour liquid Difficulty swallowing A sensation of a lump in your throat Several factors can exacerbate acid reflux, such as obesity, dietary choices, smoking, and certain medications

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Patients treated with device 1 showed a near 6-point improvement in performance on ADAS-Cog 12 and CSF A and tau ratios at 18 months, indicating the importance of the intranasal delivery device [159]