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Despite decades of research, no cure exists, and current treatments focus primarily on symptom management rather than altering the disease trajectory (Ben-Shlomo et al., 2024

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Methods Subjects At the San Diego Veterans Affairs Healthcare Service (SDVAHCS) research site, we conducted a prospective study ancillary to the national, multi-site comparative effectiveness ULT trial VA CSP594 STOP GOUT, in which gout patients were randomized to a treat to target regimen using allopurinol or the more selective XOI febuxostat [23, 24]